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Syphilis Treatments AdviceSyphilis is a sexually transmitted disease that is typically treated with antibiotics. The first treatment is usually intramuscular injections of procaine penicillin delivered on a daily basis. The actual dosage and the duration of the injections are determined by the clinical presentation of the lesion known as the chancre, any secondary mucocutaneous manifestations, etc. In the event that clinical staging cannot be done, serological stating will be used to establish the routine. For those who are allergic to penicillin, oral antibiotics such as doxycycline, tetracycline, or erythromycin may be administered for two weeks. Benzathine penicillin delivered with a single injection has been shown to treat primary and secondary syphilis. Obviously, the single injection routine is far more preferable than the ten day regime required when undertaking the procaine penicillin treatment. Also, since benzathine penicillin doesn’t traverse the blood brain barrier, it’s considered suitable in treating patients suffering in the latent stage of syphilis. On the other hand since benzathine penicillin does cross the placenta, it is considered appropriate for treating pregnant women suffering the early stage of syphilis. Those diagnosed in the late latent stage of syphilis and who cannot be certain how long they’ve been infected, as well as those with tertiary syphilis require 3 injections one week apart from each other. Once again, those who are allergic to penicillin with typically receive the alternative oral treatment of doxycycline or tetracycline. For those whose syphilis has progressed to neurosyphilis, treatment involves penicillin administered via IV every 4 hours for ten day to two week. The alternative treatment at this stage is a combination of once a day injections of penicillin with four times a day oral administrations of probenecid for up to two weeks. Even if allergic, pregnant women suffering syphilis must take penicillin. A pregnant woman with syphilis must have penicillin, even if she is allergic to it. Pregnant women who are allergic to penicillin should immediately let their doctor know about their allergic condition because they will be required to under procedures for desensitization. What is known as a Jarisch-Herxheimer reaction may occur between two and twelve hours after the beginning of penicillin treatments. Jarisch-Herxheimer reaction results from dying bacteria and can result in the worsening of symptoms, though the reaction typically ends within twenty-four hours. |
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